Synopsis Of Research:
Retinopathy of prematurity (ROP) is a disease of the developing retinal vasculature in the premature retina. There have been a number of NIH sponsored clinical trials in ROP: CRYO-ROP; LIGHT-ROP; STOP-ROP; and ET-ROP. These trials have yielded a wealth of information and publications on treatment, natural history, incidence, screening, criteria, and more. Dr. Reynolds has actively participated in all these trials, leading the LIGHT-ROP trial, and co-authored numerous papers based on these trials.

Current Or Representative Publications:

Reynolds JD, Dobson V, Quinn, GE, Fielder, AR, Palmer, EA, et al. Evidence-Based Screening criteria for Retinopathy of Prematurity: Natural-History Data from the CRYO-ROP and LIGHT-ROP Studies. Archives of Ophthalmology 2002; 120:1470-1476.

Phan, MH, Nguyen, PN, Reynolds, JD. Incidence and Severity of Retinopathy of Prematurity in Vietnam, A Developing Middle Income Country. J Ped Ophthalmology & Strabismus 2003; 40:208-212. Section on Ophthalmology, American Academy of Pediatrics, American Academy of Ophthalmology, and American Association of Pediatric Ophthalmology and Strabismus. Screening examination of premature infants for retinopathy of prematurity. Pediatrics 2006; 117:572-576.

Reynolds JD. Malpractice and the quality of care in retinopathy of prematurity (An American Ophthalmological Society Thesis). Trans Am Ophthalmol Soc 2007; 105:461-480.

Reynolds, JD; Hardy, RJ; Kennedy, KA; Spencer, R; Van Heuven, WAJ; Fielder AR; The Light Reduction in Retinopathy of Prematurity Cooperative Group: Lack of efficacy of light reduction in preventing retinopathy of prematurity. N Engl J Med. 1998; 338: 1572-1576.