Michael Zuber PhD
SUNY Upstate, Ophthalmology and Biochemistry & Molecular Biology
Current Position: Assistant Professor of Ophthalmology
Keywords Research Areas: Eye formation, eye field, eye development, retinal stem cell, retinal progenitor cell
Research Focus:
  • Retinal Diseases
  • Retinal Neuroscience
Clinical Relevance:
  • Age-Related Macular Degeneration
  • Hereditary Eye Diseases
  • Neuro-Ophthalmology
  • Retinitis Pigmentosa/Retinal Degenerations
Synopsis Of Research:

The molecular and cellular mechanisms of eye formation, the basis of retinal stem cell formation during development, mechanism regulating retinal stem/progenitor cell proliferation and the use retinal stem/progenitor cells to heal the injured or degenerating retina.

Current Or Representative Publications:
Choi RY, Engbretson GA, Solessio EC, Jones GA, Coughlin A et al. (2011) Cone Degeneration Following Rod Ablation in a Reversible Model of Retinal Degeneration. Invest Ophthalmol Vis Sci 52: 364-373.

Viczian AS, Solessio EC, Lyou Y, Zuber ME. Generation of functional eyes from pluripotent cells. PLoS Biol. 2009;7:e1000174.

Viczian AS, Bang AG, Harris WA, Zuber ME. Expression of Xenopus laevis Lhx2 during eye development and evidence for divergent expression among vertebrates. Dev Dyn. 2006;235:1133-1141.

Zuber ME, Gestri G, Viczian AS, Barsacchi G, Harris WA. Specification of the vertebrate eye by a network of eye field transcription factors. Development. 2003;130:5155-5167.

Zuber ME, Perron M, Philpott A, Bang A, Harris WA. Giant eyes in Xenopus laevis by overexpression of XOptx2. Cell. 1999;98:341-352. Zuber ME, Perron M, Philpott A, Bang A, Harris WA. Giant eyes in Xenopus laevis by overexpression of XOptx2. Cell. 1999;98:341-352.

Research:

Visit Dr. Zuber's lab web page through the Center for Vision Research at Upstate Medical University

State University of New York Medical Centers & College of Optometry Consortium

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